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38 |
 |
| |
New Therapeutic Options for Chronic Stable Angina
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 |
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 |
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39 |
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| |
New mechanistic approaches to chronic stable angina
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40 |
|
| |
Evaluation of fasudil in stable angina: Trial design
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41 |
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| |
Results: Fasudil improves exercise duration
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42 |
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| |
Results: Fasudil improves exercise time to > 1 mm ST depression
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44 |
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| |
TACT: Trimetazidine reduces angina episodes
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46 |
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| |
IONA: Reduction in primary outcome
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47 |
|
| |
INITIATIVE: Study design
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48 |
|
| |
INITIATIVE: Effects of ivabradine vs β-blockade on primary outcome
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50 |
|
| |
Ranolazine: Late Na+ current inhibitor
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51 |
|
| |
Ranolazine: Pathophysiologic effects vs older antianginals
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52 |
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| |
MARISA: Study overview
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54 |
|
| |
MARISA: Dose-related increase in exercise duration with ranolazine
|
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55 |
|
| |
MARISA: Tolerability of treatments
|
|
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57 |
|
| |
Antianginals: Effects on exercise duration
|
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58 |
|
| |
CARISA: Study overview
|
|
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|
|
|
|
|
60 |
|
| |
CARISA: Ranolazine increases exercise duration
|
|
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61 |
|
| |
CARISA: Ranolazine reduces angina frequency
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62 |
|
| |
CARISA: Ranolazine reduces nitrate consumption
|
|
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65 |
|
| |
ERICA: Ranolazine reduces angina frequency and nitrate consumption
|
|
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|
67 |
|
| |
Ranolazine: Long-term use
|
|
|
|
|
|
|
68 |
|
| |
Ranolazine extended-release tablets: Approved Jan 31, 2006
|
|
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|
|
|
|
69 |
|
| |
Ranolazine: Drug interactions
|
|
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|
|
|
|
70 |
|
| |
Ranolazine extended-release tablets: Dosing
|
|
|
|
|
|
|
71 |
|
| |
Electrophysiologic effects of ranolazine
|
|
|
|
|
|
|
72 |
|
| |
Late INa effect mitigates IKr effect
|
|
|
|
|
|
|
73 |
|
| |
Overview of torsade de pointes
|
|
|
|
|
|
|
74 |
|
| |
Ranolazine: No apparent proarrhythmic characteristics
|
|
|
|
|
|
|
75 |
|
| |
Current nonpharmacologic antianginal strategies
|
|
|
|
|
|
|
76 |
|
| |
Potential cardioprotective benefits of exercise
|
|
|
|
|
|
|
77 |
|
| |
Exercise vs PCI in low-risk CAD
|
|
|
|
|
|
|
78 |
|
| |
EECP improves angina class
|
|
|
|
|
|
|
79 |
|
| |
Surgical laser TMR improves angina class
|
|
|
|
|
|
|
80 |
|
| |
SCS vs CABG: Equivalent symptom relief in high-risk patients
|
|
|
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|
|
|
Resources
