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Slide Lecture Programs
2006 Core Curriculum
Contemporary Management of Myocardial Ischemia
May 17, 2006


V: New Therapeutic Options for Chronic Stable Angina Slide 60


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CARISA: Ranolazine increases exercise duration

  • Ranolazine SR doses of 750 mg bid and 1000 mg bid significantly increased exercise duration at trough (data shown) and peak (data not shown) compared with placebo.

  • Exercise duration at trough was similar for both doses of ranolazine compared with placebo. Improved exercise duration persisted throughout the 12-week period.

  • Benefit was additive to background therapy with traditional antianginals.


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