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Slide Lecture Programs
2006 Core Curriculum
Contemporary Management of Myocardial Ischemia
May 17, 2006


V: New Therapeutic Options for Chronic Stable Angina Slide 53


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MARISA: Study design

  • During the 2-week, single-blind placebo qualifying phase, patients underwent a baseline exercise treadmill test (ET).

  • Patients were then randomized to receive ranolazine SR 500 mg bid, 1000 mg bid, 1500 mg bid, or placebo. The 4-week active treatment period included 4 crossover periods each lasting 1 week. During this time, patients underwent weekly exercise testing at both at trough and peak.


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