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Slide Lecture Programs
2006 Core Curriculum
Contemporary Management of Myocardial Ischemia
May 17, 2006


V: New Therapeutic Options for Chronic Stable Angina Slide 46


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IONA: Reduction in primary outcome

  • The primary outcome rate was 15.5% in the placebo group and 13.1% in the nicorandil group, corresponding to a 17% relative risk reduction (hazard ratio, 0.83; 95% CI, 0.72-0.97; P = 0.014).

  • There was a significant 21% relative risk reduction in CHD death, MI, or unstable angina (P = 0.028, data not shown).

  • IONA provided the first evidence for reduction in clinical events with a novel antianginal in patients with stable angina.


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