These materials extend the knowledge presented in the four previous programs that helped define the endothelium as a mediator of cardiovascular function and structure. Endothelial function is now recognized as critically important in the pathogenesis of atherosclerosis and other cardiovascular conditions. The endothelium is also considerably influenced by cardiovascular risk factors, including hypertension, insulin resistance, and lipids. As our understanding of the pathophysiology of cardiovascular disease is revised, our treatment algorithms should also be updated. This program covers current knowledge concerning the pathophysiology and clinical trials assessing treatments based on this knowledge.
The outline that follows is keyed to the slides. For each slide you will find succinct content points: