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Core Curriculum

• Impact of vascular biology on cardiovascular disease, risk prevention, and treatment Section II: Blunting the atherosclerotic process: The case for aggressive lipid management

The VBWG Core Curriculum 2004: Impact of vascular biology on cardiovascular disease, risk prevention, and treatment. Volume VI. This edition of the core curriculum is special, because it marks the 10th anniversary of the Vascular Biology Working Group. It covers basic science and clinical advances in vascular biology in a spectrum of disorders. The material is presented in five sections:




04CoreLipidsS001.ppt

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Interaction of hypercholesterolemia and inflammation in atherogenesis

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Interaction of hypercholesterolemia and inflammation in atherogenesis Most common type of vulnerable plaque VBWG VBWG Statins reduce C-reactive protein Statins downregulate soluble CD40L: Effect is independent of lipid lowering Circulating endothelial progenitor-cell count correlates with total CV risk and endothelial function Endothelial progenitor-cell count is significantly related to total cholesterol, LDL-C, hypertension, and diabetes Statin therapy increases circulating endothelial progenitor cells in patients with Statin improves endothelium-dependent blood flow in patients with LDL <130 mg/dL Pleiotropic effects of statins on the vessel wall Apolipoproteins and HDL in practice: Maintaining a clinical focus Statin treatment following coronary artery stenting improves 1-year survival Benefit of statin therapy before PCI may be greatest with high CRP Statins benefit cardiac transplant patients with normal cholesterol or mild hypercholesterolemia Statin therapy prevents progression of endothelial dysfunction in cardiac transplant patients Evidence for statin benefit on post-transplant clinical outcome VBWG

04CoreLipidsS003.ppt

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04CoreLipidsS004.ppt

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04CoreLipidsS005.ppt

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Published by Medical Education Consultants, LLC (MEDCON), on behalf of the University of Florida College of Medicine.

The editorial content of this program does not necessarily reflect the views or recommendations of the University of Florida College of Medicine or AstraZeneca, King Pharmaceuticals Inc, Pfizer Inc, and Wyeth Pharmaceuticals, or the publisher. The reader is advised to consult the full prescribing information of each product prior to use.

This program was prepared and produced by Medical Education Consultants, LLC, Westport, Connecticut, on behalf of the University of Florida College of Medicine through an unrestricted educational grant provided by AstraZeneca, King Pharmaceuticals Inc, Pfizer Inc, and Wyeth Pharmaceuticals.

©2004 Medical Education Consultants, LLC (MEDCON). All rights reserved.

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Core Curriculum

Impact of vascular biology on cardiovascular disease, risk prevention, and treatment Section IV - Update: RAAS manipulation and cardiovascular risk--Hope for Peace?

The VBWG Core Curriculum 2004: Impact of vascular biology on cardiovascular disease, risk prevention, and treatment.

Core Curriculum

Impact of vascular biology on cardiovascular disease, risk prevention, and treatment Section V: Multiple risk and CV disease prevention

The VBWG Core Curriculum 2004: Impact of vascular biology on cardiovascular disease, risk prevention, and treatment.

Core Curriculum

Impact of vascular biology on cardiovascular disease, risk prevention, and treatment Section IV: RAAS manipulation and cardiovascular risk

The VBWG Core Curriculum 2004: Impact of vascular biology on cardiovascular disease, risk prevention, and treatment.
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